RAF Typhoon FGR4s have conducted a mission with French aircraft in a combined operation against an hidden munitions depot in Syrian territory employed by the IS group, as stated by the UK's MoD.
The location, identified by surveillance, was assessed as housing weapons and explosive materials, the release indicated, and was situated in mountainous terrain just north of Palmyra in central Syria.
"The RAF jets employed Paveway IV guided bombs to hit a number of entry passages leading to the depot... initial indications are that the objective was successfully hit," officials stated.
There was no evidence of any harm to civilians in the attack on Saturday evening and each participating jet returned safely, the ministry further stated.
The Typhoon fighters were assisted by a Voyager aerial refuelling aircraft.
IS - referred to as ISIS - enforced extremist governance over parts of Syria and Iraq until 2019.
"This strike underscores the UK's leading role, and determination to work closely with allied nations, to eradicate any re-emergence of Daesh and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey said.
UK warplanes have conducted surveillance missions over Syrian airspace to "forestall any efforts to regroup" of IS subsequent to its military defeat at the battle of Baghuz in 2019, the ministry said.
"I must thank all the members of British forces who took part in this mission for their professionalism and their courage," he commented. "Including them were numerous UK service members on duty over the festive period. This action, to remove terrorist threats who threaten our safety, shows how our armed forces are ready to step up, throughout the year, ensuring Britain's security at home and powerful internationally."
Last December, the US military carried out what it called a "large-scale strike" targeting Daesh sites in Syria, subsequent to an attack claimed the lives of two US troops and a civilian interpreter in Palmyra.
The UN says IS still boasts between 5,000 and 7,000 combatants in Syria and Iraq.
